Searchable abstracts of presentations at key conferences in endocrinology

ea0022p366 | Diabetes | ECE2010

Disease-modifying drugs in the treatment of intermittent claudication in patients with diabetes mellitus: the pilot study

Kuzina Irina , Gurieva Irina , Smirnov Sergey , Begma Inna , Kalinchenko Svetlana

Neuropathy and ischemia play paramount roles in the pathogenesis of diabetic vascular complications. Reduced tissue blood flow in experimental diabetic complications can be corrected by several disease-modifying drugs. Actovegin (deproteinised hemoderivative product) is considered to be a potential agent to stimulate cellular energy metabolism and improve cell function. Testosterone vascular effects can be mediated via increasing cardiac and muscle activity and endothelium dep...